Sathorn - home to the city's highest concentration of modern high-rises, upscale hotels, serviced apartments, office buildings, and consulates and embassies. The road is one of Bangkok's main thoroughfares, stretching from the central business district to Thonburi district on the west bank of the Chao Phraya River. This unique layout, along with the cutting-edge scenery of modern skyscrapers, makes Sathorn a popular backdrop among local filmmakers.

All Seasons Sathorn enjoys an excellent location on the southbound section of Sathorn Road. Access to the BTS skytrain and MRT subway stations is a short stroll towards Lumpini Park, at Sathorn intersection where the vibrant business and commercial district of Silom culminates. From the hotel, Silom is also accessible via a ten-minute stroll through the tree-shaded Soi Saladaeng.